Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.P20A

c.58C>G

Surrounding Variants

1 paper

NM_000616.5

p.A21T

c.61G>A

1 paper

NM_000616.5

p.A21V

c.62C>T

1 paper

NM_000616.5

p.A22P

c.64G>C

1 paper

NM_000616.5

p.A22D

c.65C>A

1 paper

NM_000616.5

p.A22V

c.65C>T

1 paper

NM_000616.5

p.T23A

c.67A>G

1 paper

NM_000616.5

p.T23T

c.69T>A

1 paper

NM_000616.5

p.Q24R

c.71A>G

5 papers

NM_000616.5

p.Q24L

c.71A>T

1 paper

NM_000616.5

p.K26E

c.76A>G

1 paper

NM_000616.5

p.K26N

c.78G>C

1 paper

NM_000616.5

p.K26N

c.78G>T