Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.C41*

c.123T>A

Surrounding Variants

1 paper

NM_000616.5

p.T42A

c.124A>G

1 paper

NM_000616.5

p.T40A

c.118A>G

1 paper

NM_000616.5

p.A43insFs

c.129dupT

1 paper

NM_000616.5

p.S44S

c.132C>A

1 paper

NM_000616.5

p.E38A

c.113A>C

1 paper

NM_000616.5

p.V37V

c.111G>C

1 paper

NM_000616.5

p.V37E

c.110T>A

1 paper

NM_000616.5

p.K46T

c.137A>C

1 paper

NM_000616.5

p.K46R

c.137A>G

1 paper

NM_000616.5

p.K46M

c.137A>T

1 paper

NM_000616.5

p.D35Y

c.103G>T

1 paper

NM_000616.5

p.D35_S44del10

c.103_131del30