Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.Q58L

c.173A>T

Surrounding Variants

1 paper

NM_000616.5

p.Q58*

c.172C>T

1 paper

NM_000616.5

p.N57S

c.170A>G

2 papers

NM_000616.5

p.S56S

c.168C>A

1 paper

NM_000616.5

p.N55K

c.165C>A

1 paper

NM_000616.5

p.K54E

c.160A>G

1 paper

NM_000616.5

p.W53*

c.158G>A

1 paper

NM_000616.5

p.W53R

c.157T>A

1 paper

NM_000616.5

p.H52P

c.155A>C

1 paper

NM_000616.5

p.N64S

c.191A>G

1 paper

NM_000616.5

p.H52L

c.155A>T

1 paper

NM_000616.5

p.N64K

c.192T>G

1 paper

NM_000616.5

p.F51L

c.153C>A