Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.G236D

c.707G>A

Surrounding Variants

1 paper

NM_000616.5

p.G234_S235ins7

c.700_704ins21

1 paper

NM_000616.5

p.L232L

c.696G>A

1 paper

NM_000616.5

p.K231K

c.693G>A

1 paper

NM_000616.5

p.A242G

c.725C>G

1 paper

NM_000616.5

p.T228I

c.683C>T

1 paper

NM_000616.5

p.F227S

c.680T>C

1 paper

NM_000616.5

p.A226A

c.678C>T

2 papers

NM_000616.5

p.S246F

c.737C>T

1 paper

NM_000616.5

p.P224A

c.670C>G

2 papers

NM_000616.5

p.S250delFs

c.748delT

1 paper

NM_000616.5

p.S250del1

c.748_750delTCT

2 papers

NM_000616.5

p.S222F

c.665C>T