Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_000616.5

p.Q290*

c.868C>T

Surrounding Variants

1 paper

NM_000616.5

p.L284L

c.850C>T

1 paper

NM_000616.5

p.T283N

c.848C>A

1 paper

NM_000616.5

p.L299P

c.896T>C

1 paper

NM_000616.5

p.A300_V315delFs

c.899_944del46

1 paper

NM_000616.5

p.L278F

c.832C>T

1 paper

NM_000616.5

p.K277R

c.830A>G

1 paper

NM_000616.5

p.K276E

c.826A>G

1 paper

NM_001195015.3

p.M1V

c.1A>G

1 paper

NM_000616.5

p.Q273Q

c.819G>A

1 paper

NM_000616.5

p.Q310*

c.928C>T

2 papers

NM_000616.5

p.V266I

c.796G>A

7 papers

NM_000616.5

p.R265W

c.793C>T