Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.G403V

c.1208G>T

Surrounding Variants

1 paper

NM_000616.5

p.V401M

c.1201G>A

1 paper

NM_000616.5

p.L409_L410delFs

c.1225_1229del5

1 paper

NM_000616.5

p.A398T

c.1192G>A

1 paper

NM_000616.5

p.A398delFs

c.1193delC

1 paper

NM_000616.5

p.M397_A398insFs

c.1191_1192insG

2 papers

NM_000616.5

p.Q395_P396insFs

c.1185_1186insC

1 paper

NM_000616.5

p.I412T

c.1235T>C

1 paper

NM_000616.5

p.L414delFs

c.1240delC

1 paper

NM_000616.5

p.T389I

c.1166C>T

1 paper

NM_000616.5

p.V420I

c.1258G>A

3 papers

NM_000616.5

p.V386Splc

c.1157-1G>A

2 papers

NM_000616.5

p.C422S

c.1264T>A