Varaico: Literature-Extracted Genetic Variants

CD74

284 papers

RefSeq Summary

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves a...

Pfam Domains

MHC2-interactaa 17–129UCSCCLIP, MHC2 interacting

MHCassoc_trimeraa 136–204UCSCClass II MHC-associated invariant chain trimerisation domain

Thyroglobulin_1aa 208–271UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

CD74 molecule

HGNC Previous Symbol

DHLAG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001025159.3

p.Q75L

c.224A>T

Surrounding Variants

1 paper

NM_001025159.3

p.Q74P

c.221A>C

1 paper

NM_001025159.3

p.A68T

c.202G>A

1 paper

NM_001025159.3

p.T84I

c.251C>T

1 paper

NM_001025159.3

p.A65G

c.194C>G

2 papers

NM_001025159.3

p.A62V

c.185C>T

1 paper

NM_001025159.3

p.L90M

c.268C>A

1 paper

NM_001025159.3

p.E91A

c.272A>C

1 paper

NM_001025159.3

p.T58T

c.174T>A

1 paper

NM_001025159.3

p.V57A

c.170T>C

1 paper

NM_001025159.3

p.V57E

c.170T>A

1 paper

NM_001025159.3

p.R94C

c.280C>T

1 paper

NM_001025159.3

p.R94H

c.281G>A