Varaico: Literature-Extracted Genetic Variants

Gene:CD80
Variant:p.T135A

CD80

281 papers

RefSeq Summary

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can...

Pfam Domains

V-setaa 36–137UCSCImmunoglobulin V-set domain
C2-set_2aa 141–227UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD80 molecule

HGNC Previous Symbols

CD28LG; CD28LG1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005191.4
p.T135A
c.403A>G
Surrounding Variants
1 paper
NM_005191.4
p.E133V
c.398A>T
1 paper
NM_005191.4
p.V138F
c.412G>T
1 paper
NM_005191.4
p.L131P
c.392T>C
1 paper
NM_005191.4
p.H130R
c.389A>G
2 papers
NM_005191.4
p.E129G
c.386A>G
1 paper
NM_005191.4
p.R128W
c.382C>T
1 paper
NM_005191.4
p.D124E
c.372C>G
1 paper
NM_005191.4
p.D124E
c.372C>A
1 paper
NM_005191.4
p.E122G
c.365A>G
1 paper
NM_005191.4
p.L119R
c.356T>G
1 paper
NM_005191.4
p.V118I
c.352G>A
1 paper
NM_005191.4
p.E115*
c.343G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."