Varaico: Literature-Extracted Genetic Variants

Gene:CD80
Variant:p.N89K

CD80

281 papers

RefSeq Summary

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can...

Pfam Domains

V-setaa 36–137UCSCImmunoglobulin V-set domain
C2-set_2aa 141–227UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD80 molecule

HGNC Previous Symbols

CD28LG; CD28LG1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005191.4
p.N89K
c.267C>G
Surrounding Variants
1 paper
NM_005191.4
p.N89K
c.267C>A
1 paper
NM_005191.4
p.N98T
c.293A>C
3 papers
NM_005191.4
p.D80N
c.238G>A
1 paper
NM_005191.4
p.G79insFs
c.236_237ins7
1 paper
NM_005191.4
p.S78S
c.234T>A
1 paper
NM_005191.4
p.M77L
c.229A>C
1 paper
NM_005191.4
p.L74M
c.220C>A
1 paper
NM_005191.4
p.L106R
c.317T>G
1 paper
NM_005191.4
p.M72I
c.216G>T
1 paper
NM_005191.4
p.M72I
c.216G>C
1 paper
NM_005191.4
p.M72I
c.216G>A
1 paper
NM_005191.4
p.M72T
c.215T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."