Varaico: Literature-Extracted Genetic Variants

CDC25A

135 papers

RefSeq Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosp...

Pfam Domains

M-inducer_phospaa 86–328UCSCM-phase inducer phosphatase

Rhodaneseaa 369–476UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25A

HGNC Alias Names

CDC25 homolog A (S. pombe); M-phase inducer phosphatase 1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 95 variants

3 papers

NM_001789.3

p.Q24H

c.72G>T

3 papers

NM_001789.3

p.Q24H

c.72G>C

3 papers

NM_001789.3

p.S88F

c.263C>T

3 papers

NM_001789.3

p.F218I

c.652T>A

3 papers

NM_001789.3

p.S367delFs

c.1100delG

2 papers

NM_001789.3

p.H9N

c.25C>A

2 papers

NM_001789.3

p.S76A

c.226T>G

2 papers

NM_001789.3

p.S82A

c.244T>G

2 papers

NM_001789.3

p.G83Splc

c.247+1G>A

2 papers

NM_001789.3

p.S88A

c.262T>G

2 papers

NM_001789.3

p.R182W

c.544C>T

2 papers

NM_001789.3

p.R182G

c.544C>G