Varaico: Literature-Extracted Genetic Variants

CDC25A

135 papers

RefSeq Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosp...

Pfam Domains

M-inducer_phospaa 86–328UCSCM-phase inducer phosphatase

Rhodaneseaa 369–476UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25A

HGNC Alias Names

CDC25 homolog A (S. pombe); M-phase inducer phosphatase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001789.3

p.C431S

c.1291T>A

Surrounding Variants

2 papers

NM_001789.3

p.C431S

c.1292G>C

1 paper

NM_001789.3

p.V427_V428insA

c.1279_1283ins3

1 paper

NM_001789.3

p.E436K

c.1306G>A

1 paper

NM_001789.3

p.V425V

c.1275C>A

1 paper

NM_001789.3

p.P439L

c.1316C>T

1 paper

NM_001789.3

p.G394S

c.1180G>A

1 paper

NM_001789.3

p.E392D

c.1176G>T

1 paper

NM_001789.3

p.E392D

c.1176G>C

3 papers

NM_001789.3

p.S367delFs

c.1100delG

1 paper

NM_001789.3

p.A366P

c.1096G>C

1 paper

NM_001789.3

p.T349P

c.1045A>C

1 paper

NM_001789.3

p.K343_G344Splc

c.1030-5T>A