Varaico: Literature-Extracted Genetic Variants

CDC25A

135 papers

RefSeq Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosp...

Pfam Domains

M-inducer_phospaa 86–328UCSCM-phase inducer phosphatase

Rhodaneseaa 369–476UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25A

HGNC Alias Names

CDC25 homolog A (S. pombe); M-phase inducer phosphatase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001789.3

p.S185F

c.554C>T

Surrounding Variants

1 paper

NM_001789.3

p.S186A

c.556T>G

1 paper

NM_001789.3

p.N187delins

c.560_561delinsTG

1 paper

NM_001789.3

p.R189insFs

c.566_567insA

1 paper

NM_001789.3

p.L211S

c.632T>C

1 paper

NM_001789.3

p.S212A

c.634T>G

1 paper

NM_001789.3

p.D216A

c.647A>C

3 papers

NM_001789.3

p.F218I

c.652T>A

1 paper

NM_001789.3

p.D220Y

c.658G>T

1 paper

NM_001789.3

p.D220N

c.658G>A

1 paper

NM_001789.3

p.D223A

c.668A>C

2 papers

NM_001789.3

p.R182W

c.544C>T

2 papers

NM_001789.3

p.R182G

c.544C>G