Varaico: Literature-Extracted Genetic Variants

CDC25A

135 papers

RefSeq Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosp...

Pfam Domains

M-inducer_phospaa 86–328UCSCM-phase inducer phosphatase

Rhodaneseaa 369–476UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25A

HGNC Alias Names

CDC25 homolog A (S. pombe); M-phase inducer phosphatase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001789.3

p.R182G

c.544C>G

Surrounding Variants

2 papers

NM_001789.3

p.R182W

c.544C>T

1 paper

NM_001789.3

p.S178A

c.532T>G

1 paper

NM_001789.3

p.K169R

c.506A>G

1 paper

NM_001789.3

p.S162T

c.484T>A

1 paper

NM_001789.3

p.C159Y

c.476G>A

1 paper

NM_001789.3

p.K150R

c.449A>G

1 paper

NM_001789.3

p.N143insFs

c.427_428insA

1 paper

NM_001789.3

p.I131V

c.391A>G

1 paper

NM_001789.3

p.L127V

c.379C>G

1 paper

NM_001789.3

p.S124A

c.370T>G

1 paper

NM_001789.3

p.P117L

c.350C>T

1 paper

NM_001789.3

p.Q110del1

c.328_329delCTG