Varaico: Literature-Extracted Genetic Variants

CDC25A

135 papers

RefSeq Summary

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosp...

Pfam Domains

M-inducer_phospaa 86–328UCSCM-phase inducer phosphatase

Rhodaneseaa 369–476UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25A

HGNC Alias Names

CDC25 homolog A (S. pombe); M-phase inducer phosphatase 1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001789.3

p.P20S

c.58C>T

Surrounding Variants

1 paper

NM_001789.3

p.P21A

c.61C>G

1 paper

NM_001789.3

p.C17W

c.51C>G

3 papers

NM_001789.3

p.Q24H

c.72G>T

3 papers

NM_001789.3

p.Q24H

c.72G>C

1 paper

NM_001789.3

p.V26A

c.77T>C

1 paper

NM_001789.3

p.R12H

c.35G>A

1 paper

NM_001789.3

p.R10insFs

c.28_29insT

2 papers

NM_001789.3

p.H9N

c.25C>A

1 paper

NM_001789.3

p.P5L

c.14C>T

1 paper

NM_001789.3

p.L3delFs

c.8delA

1 paper

NM_001789.3

p.M1_E2insFs

c.3_4insA

1 paper

NM_001789.3

p.L39M

c.115C>A