Varaico: Literature-Extracted Genetic Variants

CDC25B

79 papers

RefSeq Summary

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles be...

Pfam Domains

M-inducer_phospaa 49–319UCSCM-phase inducer phosphatase

M-inducer_phospaa 214–292UCSCM-phase inducer phosphatase

Rhodaneseaa 361–467UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25B

HGNC Alias Symbol

MPIP2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021873.4

p.E216K

c.646G>A

Surrounding Variants

1 paper

NM_021873.4

p.E222G

c.665A>G

1 paper

NM_021873.4

p.P205L

c.614C>T

2 papers

NM_021873.4

p.S230P

c.688T>C

1 paper

NM_021873.4

p.S230A

c.688T>G

1 paper

NM_021873.4

p.M243R

c.728T>G

1 paper

NM_021873.4

p.S169A

c.505T>G

1 paper

NM_021873.4

p.E246K

c.736G>A

1 paper

NM_021873.4

p.V272M

c.814G>A

1 paper

NM_021873.4

p.E142G

c.425A>G

1 paper

NM_021873.4

p.R140P

c.419G>C

1 paper

NM_021873.4

p.R137W

c.409C>T

1 paper

NM_021873.4

p.I132T

c.395T>C