Varaico: Literature-Extracted Genetic Variants

Gene:CDC25C
Variant:p.N399S

CDC25C

175 papers

RefSeq Summary

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It...

Pfam Domains

M-inducer_phospaa 190–271UCSCM-phase inducer phosphatase
Rhodaneseaa 307–421UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25C

HGNC Previous Symbol

CDC25

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001790.5
p.N399S
c.1196A>G
Surrounding Variants
1 paper
NM_001790.5
p.P402A
c.1204C>G
1 paper
NM_001790.5
p.D395E
c.1185C>G
1 paper
NM_001790.5
p.D395E
c.1185C>A
1 paper
NM_001790.5
p.R392H
c.1175G>A
1 paper
NM_001790.5
p.R389H
c.1166G>A
1 paper
NM_001790.5
p.P421S
c.1261C>T
1 paper
NM_001790.5
p.P421T
c.1261C>A
1 paper
NM_001790.5
p.H437N
c.1309C>A
1 paper
NM_001790.5
p.L445P
c.1334T>C
1 paper
NM_001790.5
p.R458W
c.1372C>T
1 paper
NM_001790.5
p.R461Q
c.1382G>A
1 paper
NM_001790.5
p.D470N
c.1408G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."