Varaico: Literature-Extracted Genetic Variants

Gene:CDC25C
Variant:p.E308A

CDC25C

175 papers

RefSeq Summary

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It...

Pfam Domains

M-inducer_phospaa 190–271UCSCM-phase inducer phosphatase
Rhodaneseaa 307–421UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25C

HGNC Previous Symbol

CDC25

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001790.5
p.E308A
c.923A>C
Surrounding Variants
1 paper
NM_001790.5
p.K303insFs
c.908dupA
5 papers
NM_001790.5
p.G297R
c.889G>C
5 papers
NM_001790.5
p.G297R
c.889G>A
1 paper
NM_001790.5
p.S287A
c.859T>G
1 paper
NM_001790.5
p.I283V
c.847A>G
1 paper
NM_001790.5
p.E274D
c.822G>T
1 paper
NM_001790.5
p.L264V
c.790C>G
1 paper
NM_001790.5
p.S263A
c.787T>G
1 paper
NM_001790.5
p.T261I
c.782C>T
1 paper
NM_001790.5
p.L313_K317del5
c.937_950del15
1 paper
NM_001790.5
p.G320D
c.959G>A
1 paper
NM_001790.5
p.R331H
c.992G>A
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