Varaico: Literature-Extracted Genetic Variants

Gene:CDC25C
Variant:p.R10delFs

CDC25C

175 papers

RefSeq Summary

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It...

Pfam Domains

M-inducer_phospaa 190–271UCSCM-phase inducer phosphatase
Rhodaneseaa 307–421UCSCRhodanese-like domain

Gene Aliases

HGNC Name

cell division cycle 25C

HGNC Previous Symbol

CDC25

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001790.5
p.R10delFs
c.28delT
Surrounding Variants
1 paper
NM_001790.5
p.E12Q
c.34G>C
2 papers
NM_001790.5
p.S14N
c.41G>A
1 paper
NM_001790.5
p.S14R
c.42C>A
1 paper
NM_001790.5
p.L5_F6insG
c.13_17ins3
1 paper
NM_001790.5
p.S17P
c.49T>C
1 paper
NM_001790.5
p.S17L
c.50C>T
1 paper
NM_001790.5
p.S2delFs
c.5delG
1 paper
NM_001790.5
p.G18R
c.52G>C
1 paper
NM_001790.5
p.G18R
c.52G>A
1 paper
NM_001790.5
p.F21C
c.62T>G
1 paper
NM_001790.5
p.F21_S23del0
c.62_67del6
1 paper
NM_001790.5
p.M28del1
c.82_83delCAT
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