Varaico: Literature-Extracted Genetic Variants

CDC27

289 papers

RefSeq Summary

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaph...

Pfam Domains

ANAPC3aa 17–95UCSCAnaphase-promoting complex, cyclosome, subunit 3

TPR_1aa 567–600UCSCTetratricopeptide repeat

TPR_8aa 600–633UCSCTetratricopeptide repeat

TPR_1aa 635–668UCSCTetratricopeptide repeat

TPR_8aa 669–701UCSCTetratricopeptide repeat

Gene Aliases

HGNC Name

cell division cycle 27

HGNC Previous Symbols

D0S1430E; D17S978E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_001256.6

p.L254*

c.761T>G

Surrounding Variants

11 papers

NM_001256.6

p.L254*

c.761T>A

2 papers

NM_001256.6

p.L254F

c.762A>T

2 papers

NM_001256.6

p.L254F

c.762A>C

3 papers

NM_001256.6

p.S252T

c.754T>A

15 papers

NM_001256.6

p.N260H

c.778A>C

1 paper

NM_001256.6

p.N260S

c.779A>G

1 paper

NM_001256.6

p.N260_K261ins5

c.780_781ins15

1 paper

NM_001256.6

p.K261ins1

c.781_782insGGG

2 papers

NM_001256.6

p.V245L

c.733G>C

4 papers

NM_001256.6

p.T264P

c.790A>C

2 papers

NM_001256.6

p.G265D

c.794G>A

2 papers

NM_001256.6

p.R266*

c.796C>T