Varaico: Literature-Extracted Genetic Variants

CDC6

139 papers

RefSeq Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps...

Pfam Domains

AAA_16aa 171–314UCSCAAA ATPase domain

Cdc6-ORC-like_ATPase_lidaa 346–405UCSCCdc6/ORC-like, ATPase lid domain

WHD_Cdc6aa 452–544UCSCCDC6, C terminal winged helix domain

Gene Aliases

HGNC Name

cell division cycle 6

HGNC Previous Symbol

CDC18L

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001254.4

p.P2H

c.5C>A

Surrounding Variants

1 paper

NM_001254.4

p.P2P

c.6T>A

1 paper

NM_001254.4

p.M1T

c.2T>C

1 paper

NM_001254.4

p.R5*

c.13C>T

1 paper

NM_001254.4

p.Q7E

c.19C>G

1 paper

NM_001254.4

p.K33del1

c.97_98delAAA

1 paper

NM_001254.4

p.K33E

c.97A>G

1 paper

NM_001254.4

p.K33R

c.98A>G

1 paper

NM_001254.4

p.S45delFs

c.134delC

1 paper

NM_001254.4

p.S45fs

c.133_134fs

1 paper

NM_001254.4

p.S54R

c.160A>C

1 paper

NM_001254.4

p.S54C

c.160A>T

1 paper

NM_001254.4

p.H69Y

c.205C>T