Varaico: Literature-Extracted Genetic Variants

CDC6

139 papers

RefSeq Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps...

Pfam Domains

AAA_16aa 171–314UCSCAAA ATPase domain

Cdc6-ORC-like_ATPase_lidaa 346–405UCSCCdc6/ORC-like, ATPase lid domain

WHD_Cdc6aa 452–544UCSCCDC6, C terminal winged helix domain

Gene Aliases

HGNC Name

cell division cycle 6

HGNC Previous Symbol

CDC18L

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001254.4

p.E285A

c.854A>C

Surrounding Variants

1 paper

NM_001254.4

p.E285G

c.854A>G

1 paper

NM_001254.4

p.E285Q

c.853G>C

10 papers

NM_001254.4

p.D295N

c.883G>A

3 papers

NM_001254.4

p.T299M

c.896C>T

1 paper

NM_001254.4

p.W305*

c.914G>A

1 paper

NM_001254.4

p.W305*

c.915G>A

1 paper

NM_001254.4

p.I314T

c.941T>C

1 paper

NM_001254.4

p.K275N

c.825G>C

1 paper

NM_001254.4

p.K275N

c.825G>T

10 papers

NM_001254.4

p.T323R

c.968C>G

1 paper

NM_001254.4

p.D324H

c.970G>C

1 paper

NM_001254.4

p.R329M

c.986G>T