Varaico: Literature-Extracted Genetic Variants

CDC6

139 papers

RefSeq Summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps...

Pfam Domains

AAA_16aa 171–314UCSCAAA ATPase domain

Cdc6-ORC-like_ATPase_lidaa 346–405UCSCCdc6/ORC-like, ATPase lid domain

WHD_Cdc6aa 452–544UCSCCDC6, C terminal winged helix domain

Gene Aliases

HGNC Name

cell division cycle 6

HGNC Previous Symbol

CDC18L

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001254.4

p.C493delFs

c.1477delT

Surrounding Variants

1 paper

NM_001254.4

p.S490N

c.1469G>A

1 paper

NM_001254.4

p.A488T

c.1462G>A

1 paper

NM_001254.4

p.Y486F

c.1457A>T

1 paper

NM_001254.4

p.G517D

c.1550G>A

1 paper

NM_001254.4

p.G520R

c.1558G>A

1 paper

NM_001254.4

p.G520R

c.1558G>C

1 paper

NM_001254.4

p.K531T

c.1592A>C

1 paper

NM_001254.4

p.K531R

c.1592A>G

1 paper

NM_001254.4

p.I554M

c.1662C>G

1 paper

NM_001254.4

p.R473G

c.1417A>G

1 paper

NM_001254.4

p.S456A

c.1366T>G

11 papers

NM_001254.4

p.V441I

c.1321G>A