Varaico: Literature-Extracted Genetic Variants

CDC73

591 papers

RefSeq Summary

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the...

Pfam Domains

CDC73_Naa 1–297UCSCPaf1 complex subunit CDC73 N-terminal

CDC73_Caa 356–521UCSCRNA pol II accessory factor, Cdc73 family, C-terminal

Gene Aliases

HGNC Name

cell division cycle 73

HGNC Previous Symbols

C1orf28; HRPT2; HRPT1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_024529.5

p.E53*

c.157G>T

Surrounding Variants

1 paper

NM_024529.5

p.R52R

c.156A>G

1 paper

NM_024529.5

p.R52fs

c.154_155fs

27 papers

NM_024529.5

p.Y54*

c.162C>A

29 papers

NM_024529.5

p.Y54*

c.162C>G

1 paper

NM_024529.5

p.P51L

c.152C>T

1 paper

NM_024529.5

p.R52_T56delFs

c.155_168del14

1 paper

NM_024529.5

p.P51fs

c.151_152fs

3 papers

NM_024529.5

p.Y55N

c.163T>A

6 papers

NM_024529.5

p.Y55S

c.164A>C

3 papers

NM_024529.5

p.Y55C

c.164A>G

7 papers

NM_024529.5

p.Y55delFs

c.165delC

15 papers

NM_024529.5

p.Y55*

c.165C>A