Varaico: Literature-Extracted Genetic Variants

CDC73

591 papers

RefSeq Summary

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the...

Pfam Domains

CDC73_Naa 1–297UCSCPaf1 complex subunit CDC73 N-terminal

CDC73_Caa 356–521UCSCRNA pol II accessory factor, Cdc73 family, C-terminal

Gene Aliases

HGNC Name

cell division cycle 73

HGNC Previous Symbols

C1orf28; HRPT2; HRPT1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024529.5

p.V220A

c.659T>C

Surrounding Variants

1 paper

NM_024529.5

p.T221A

c.661A>G

26 papers

NM_024529.5

p.R222*

c.664C>T

1 paper

NM_024529.5

p.V218L

c.652G>C

1 paper

NM_024529.5

p.V218L

c.652G>T

1 paper

NM_024529.5

p.E217_V218delins

c.651_652delinsAT

1 paper

NM_024529.5

p.D223Fs

c.668_669delinsGFs

1 paper

NM_024529.5

p.D223delins

c.668_669delinsGG

2 papers

NM_024529.5

p.I224T

c.671T>C

1 paper

NM_024529.5

p.V225I

c.673G>A

1 paper

NM_024529.5

p.V225A

c.674T>C

8 papers

NM_024529.5

p.R229_V230insFs

c.687_688dupAG

17 papers

NM_024529.5

p.R229_V230delFs

c.687_688delAG