Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.R246C

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.R246C
c.736C>T
Surrounding Variants
1 paper
NM_000075.4
p.R246S
c.736C>A
1 paper
NM_000075.4
p.R246H
c.737G>A
1 paper
NM_000075.4
p.P245S
c.733C>T
1 paper
NM_000075.4
p.L244_P245insFs
c.732_733insG
1 paper
NM_000075.4
p.G247A
c.740G>C
1 paper
NM_000075.4
p.G247E
c.740G>A
1 paper
NM_000075.4
p.L244L
c.730C>T
1 paper
NM_000075.4
p.L244M
c.730C>A
1 paper
NM_000075.4
p.S243A
c.727T>G
1 paper
NM_000075.4
p.F249C
c.746T>G
1 paper
NM_000075.4
p.V242L
c.724G>T
1 paper
NM_000075.4
p.P250S
c.748C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."