Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.L229L

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.L229L
c.687G>A
Surrounding Variants
1 paper
NM_000075.4
p.I230L
c.688A>C
4 papers
NM_000075.4
p.I230T
c.689T>C
1 paper
NM_000075.4
p.D228Splc
c.684-1G>A
1 paper
NM_000075.4
p.D228A
c.683A>C
2 papers
NM_000075.4
p.D228Splc
c.684-4A>T
1 paper
NM_000075.4
p.L232insFs
c.695_696insT
1 paper
NM_000075.4
p.L232L
c.696G>A
1 paper
NM_000075.4
p.P234S
c.700C>T
1 paper
NM_000075.4
p.P234L
c.701C>T
1 paper
NM_000075.4
p.E235K
c.703G>A
1 paper
NM_000075.4
p.D236fs
c.706_707fs
1 paper
NM_000075.4
p.D236delFs
c.707delT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."