Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.Y180Y

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_000075.4
p.Y180Y
c.540C>T
Surrounding Variants
1 paper
NM_000075.4
p.Y180*
c.540C>G
2 papers
NM_000075.4
p.Y180H
c.538T>C
1 paper
NM_000075.4
p.R181P
c.542G>C
3 papers
NM_000075.4
p.R181Q
c.542G>A
1 paper
NM_000075.4
p.A182T
c.544G>A
2 papers
NM_000075.4
p.A182V
c.545C>T
1 paper
NM_000075.4
p.A182G
c.545C>G
3 papers
NM_000075.4
p.P183L
c.548C>T
2 papers
NM_000075.4
p.E184K
c.550G>A
1 paper
NM_000075.4
p.T177S
c.529A>T
1 paper
NM_000075.4
p.T177A
c.529A>G
1 paper
NM_000075.4
p.E184A
c.551A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."