Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.T149T

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000075.4
p.T149T
c.447A>G
Surrounding Variants
1 paper
NM_000075.4
p.T149S
c.445A>T
1 paper
NM_000075.4
p.V148A
c.443T>C
4 papers
NM_000075.4
p.V148M
c.442G>A
1 paper
NM_000075.4
p.L147Q
c.440T>A
1 paper
NM_000075.4
p.G152E
c.455G>A
1 paper
NM_000075.4
p.T153A
c.457A>G
7 papers
NM_000075.4
p.V154L
c.460G>C
1 paper
NM_000075.4
p.V154I
c.460G>A
1 paper
NM_000075.4
p.N145S
c.434A>G
1 paper
NM_000075.4
p.E144G
c.431A>G
1 paper
NM_000075.4
p.K155Q
c.463A>C
1 paper
NM_000075.4
p.E144K
c.430G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."