Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.K142N

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.K142N
c.426G>T
Surrounding Variants
1 paper
NM_000075.4
p.K142N
c.426G>C
1 paper
NM_000075.4
p.K142R
c.425A>G
1 paper
NM_000075.4
p.P143R
c.428C>G
1 paper
NM_000075.4
p.L141P
c.422T>C
1 paper
NM_000075.4
p.E144K
c.430G>A
1 paper
NM_000075.4
p.E144G
c.431A>G
2 papers
NM_000075.4
p.D140G
c.419A>G
1 paper
NM_000075.4
p.D140Y
c.418G>T
1 paper
NM_000075.4
p.D140H
c.418G>C
1 paper
NM_000075.4
p.N145S
c.434A>G
1 paper
NM_000075.4
p.R139*
c.415C>T
1 paper
NM_000075.4
p.L147Q
c.440T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."