Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.C135F

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.C135F
c.404G>T
Surrounding Variants
2 papers
NM_000075.4
p.C135S
c.404G>C
2 papers
NM_000075.4
p.C135S
c.403T>A
1 paper
NM_000075.4
p.H132_N134del3
c.394_401del9
1 paper
NM_000075.4
p.C135fs
c.403_404fs
1 paper
NM_000075.4
p.C135*
c.405C>A
1 paper
NM_000075.4
p.I136I
c.408C>T
2 papers
NM_000075.4
p.V137L
c.409G>C
3 papers
NM_000075.4
p.V137I
c.409G>A
1 paper
NM_000075.4
p.V137A
c.410T>C
1 paper
NM_000075.4
p.H132L
c.395A>T
1 paper
NM_000075.4
p.R139*
c.415C>T
1 paper
NM_000075.4
p.L131_H132insA
c.391_395ins3
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."