Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.M121I

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.M121I
c.363G>C
Surrounding Variants
1 paper
NM_000075.4
p.M121I
c.363G>T
1 paper
NM_000075.4
p.M121I
c.363G>A
1 paper
NM_000075.4
p.M121T
c.362T>C
3 papers
NM_000075.4
p.R122C
c.364C>T
1 paper
NM_000075.4
p.R122L
c.365G>T
4 papers
NM_000075.4
p.R122H
c.365G>A
1 paper
NM_000075.4
p.L120P
c.359T>C
2 papers
NM_000075.4
p.Q123*
c.367C>T
1 paper
NM_000075.4
p.L120M
c.358C>A
1 paper
NM_000075.4
p.K118_D119Splc
c.355-1G>A
1 paper
NM_000075.4
p.L125V
c.373C>G
1 paper
NM_000075.4
p.K118_D119Splc
c.355-2A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."