Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.P108L

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.P108L
c.323C>T
Surrounding Variants
1 paper
NM_000075.4
p.P109S
c.325C>T
1 paper
NM_000075.4
p.K106K
c.318G>A
3 papers
NM_000075.4
p.P110L
c.329C>T
1 paper
NM_000075.4
p.G111ins1
c.331_332insGTC
1 paper
NM_000075.4
p.D105V
c.314A>T
1 paper
NM_000075.4
p.L112L
c.334T>C
1 paper
NM_000075.4
p.L104P
c.311T>C
1 paper
NM_000075.4
p.L104M
c.310C>A
1 paper
NM_000075.4
p.Y103fs
c.307_308fs
1 paper
NM_000075.4
p.Y103*
c.309T>G
1 paper
NM_000075.4
p.Y103*
c.309T>A
1 paper
NM_000075.4
p.T102delFs
c.306delT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."