Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.R73W

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.R73W
c.217C>T
Surrounding Variants
1 paper
NM_000075.4
p.R73Splc
c.219-2A>C
1 paper
NM_000075.4
p.R73Splc
c.219-1G>C
1 paper
NM_000075.4
p.R73Q
c.218G>A
1 paper
NM_000075.4
p.L74L
c.220C>T
1 paper
NM_000075.4
p.M75V
c.223A>G
2 papers
NM_000075.4
p.D76A
c.227A>C
3 papers
NM_000075.4
p.D76D
c.228C>T
1 paper
NM_000075.4
p.C78delFs
c.234delA
1 paper
NM_000075.4
p.A79V
c.236C>T
1 paper
NM_000075.4
p.A79D
c.236C>A
1 paper
NM_000075.4
p.R73Splc
c.219-22A>T
1 paper
NM_000075.4
p.A79delFs
c.236delG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."