Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.R62*

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.R62*
c.184C>T
Surrounding Variants
1 paper
NM_000075.4
p.L60L
c.180G>A
1 paper
NM_000075.4
p.L60fs
c.178_179fs
2 papers
NM_000075.4
p.E64G
c.191A>G
1 paper
NM_000075.4
p.E64A
c.191A>C
1 paper
NM_000075.4
p.E56_L59del0
c.168_176del9
1 paper
NM_000075.4
p.L59*
c.176T>G
1 paper
NM_000075.4
p.A58fs
c.172_173fs
1 paper
NM_000075.4
p.A65V
c.194C>T
1 paper
NM_000075.4
p.A65G
c.194C>G
1 paper
NM_000075.4
p.A65A
c.195T>C
1 paper
NM_000075.4
p.A58delFs
c.172delC
2 papers
NM_000075.4
p.E67Q
c.199G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."