Varaico: Literature-Extracted Genetic Variants

Gene:CDK4
Variant:p.D25E

CDK4

1,380 papers

RefSeq Summary

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subun...

Pfam Domains

Pkinaseaa 6–295UCSCProtein kinase domain

Gene Aliases

HGNC Name

cyclin dependent kinase 4

HGNC Alias Symbol

PSK-J3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000075.4
p.D25E
c.75T>G
Surrounding Variants
2 papers
NM_000075.4
p.D25E
c.75T>A
1 paper
NM_000075.4
p.P26S
c.76C>T
3 papers
NM_000075.4
p.D25A
c.74A>C
1 paper
NM_000075.4
p.D25delFs
c.73delC
1 paper
NM_000075.4
p.D25N
c.73G>A
1 paper
NM_000075.4
p.P26L
c.77C>T
1 paper
NM_000075.4
p.P26H
c.77C>A
1 paper
NM_000075.4
p.R24delFs
c.71delC
1 paper
NM_000075.4
p.V20_P26insFs
c.59_77dup19
1 paper
NM_000075.4
p.P26fs
c.76_77fs
1 paper
NM_000075.4
p.P26P
c.78C>A
40 papers
NM_000075.4
p.R24L
c.71G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."