Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1A
Variant:p.D35E

CDKN1A

1,992 papers

RefSeq Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus...

Pfam Domains

CDIaa 20–68UCSCCyclin-dependent kinase inhibitor

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 1A

HGNC Previous Symbol

CDKN1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000389.5
p.D35E
c.105T>G
Surrounding Variants
2 papers
NM_000389.5
p.D35E
c.105T>A
1 paper
NM_000389.5
p.D35_A36insFs
c.105_106insGC
1 paper
NM_000389.5
p.A36P
c.106G>C
1 paper
NM_000389.5
p.A36fs
c.106_107fs
2 papers
NM_000389.5
p.A36V
c.107C>T
1 paper
NM_000389.5
p.D35insFs
c.104_105insA
1 paper
NM_000389.5
p.D35_Q43del0
c.104_127del24
1 paper
NM_000389.5
p.C34*
c.102T>A
1 paper
NM_000389.5
p.C34C
c.102T>C
1 paper
NM_000389.5
p.D35_Q43del9
c.103_128del27
1 paper
NM_000389.5
p.L37I
c.109C>A
2 papers
NM_000389.5
p.L37fs
c.109_110fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."