Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1A
Variant:p.S137A

CDKN1A

1,992 papers

RefSeq Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus...

Pfam Domains

CDIaa 20–68UCSCCyclin-dependent kinase inhibitor

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 1A

HGNC Previous Symbol

CDKN1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_000389.5
p.S137A
c.409T>G
Surrounding Variants
2 papers
NM_000389.5
p.S137F
c.410C>T
1 paper
NM_000389.5
p.D136D
c.408C>T
1 paper
NM_000389.5
p.Q138*
c.412C>T
1 paper
NM_000389.5
p.D136H
c.406G>C
1 paper
NM_000389.5
p.D136Y
c.406G>T
5 papers
NM_000389.5
p.G135E
c.404G>A
1 paper
NM_000389.5
p.Q138Q
c.414G>A
1 paper
NM_000389.5
p.G135A
c.404G>C
1 paper
NM_000389.5
p.G135R
c.403G>A
1 paper
NM_000389.5
p.G139S
c.415G>A
1 paper
NM_000389.5
p.G135R
c.403G>C
1 paper
NM_000389.5
p.G139R
c.415G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."