Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1B
Variant:p.P69L

CDKN1B

800 papers

RefSeq Summary

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyc...

Pfam Domains

CDIaa 31–79UCSCCyclin-dependent kinase inhibitor

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 1B

HGNC Alias Symbols

KIP1; P27KIP1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
21 papers
NM_004064.5
p.P69L
c.206C>T
Surrounding Variants
1 paper
NM_004064.5
p.P69R
c.206C>G
2 papers
NM_004064.5
p.P69S
c.205C>T
1 paper
NM_004064.5
p.P69P
c.207C>T
1 paper
NM_004064.5
p.P69_L70insFs
c.207_208ins5
3 papers
NM_004064.5
p.L70fs
c.208_209fs
1 paper
NM_004064.5
p.L70delFs
c.209delT
2 papers
NM_004064.5
p.K68R
c.203A>G
1 paper
NM_004064.5
p.K68fs
c.202_203fs
2 papers
NM_004064.5
p.K68*
c.202A>T
1 paper
NM_004064.5
p.H67Q
c.201C>A
1 paper
NM_004064.5
p.H67Q
c.201C>G
1 paper
NM_004064.5
p.E71K
c.211G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."