Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.R109C

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004936.4
p.R109C
c.325C>T
Surrounding Variants
1 paper
NM_004936.4
p.R109H
c.326G>A
1 paper
NM_004936.4
p.V108L
c.322G>C
4 papers
NM_004936.4
p.D110N
c.328G>A
3 papers
NM_004936.4
p.V108M
c.322G>A
1 paper
NM_004936.4
p.D110G
c.329A>G
1 paper
NM_004936.4
p.A111T
c.331G>A
1 paper
NM_004936.4
p.L106L
c.318G>A
1 paper
NM_004936.4
p.W112*
c.335G>A
4 papers
NM_004936.4
p.R105Q
c.314G>A
1 paper
NM_004936.4
p.W112*
c.336G>A
1 paper
NM_004936.4
p.G113S
c.337G>A
3 papers
NM_004936.4
p.R105W
c.313C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."