Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.T81N

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.T81N
c.242C>A
Surrounding Variants
1 paper
NM_004936.4
p.T81I
c.242C>T
1 paper
NM_004936.4
p.T81_R82insFs
c.243_244insA
1 paper
NM_004936.4
p.R82*
c.244C>T
1 paper
NM_004936.4
p.A75_T81delFs
c.225_243del19
1 paper
NM_004936.4
p.L80P
c.239T>C
1 paper
NM_004936.4
p.R82P
c.245G>C
1 paper
NM_004936.4
p.R82R
c.246A>T
2 papers
NM_004936.4
p.P83S
c.247C>T
1 paper
NM_004936.4
p.P83A
c.247C>G
1 paper
NM_004936.4
p.P83L
c.248C>T
1 paper
NM_004936.4
p.T79I
c.236C>T
1 paper
NM_004936.4
p.T79A
c.235A>G
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