Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.D76D

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_004936.4
p.D76D
c.228C>T
Surrounding Variants
1 paper
NM_004936.4
p.P77S
c.229C>T
1 paper
NM_004936.4
p.D76A
c.227A>C
1 paper
NM_004936.4
p.D76Y
c.226G>T
1 paper
NM_004936.4
p.A78T
c.232G>A
1 paper
NM_004936.4
p.A75T
c.223G>A
1 paper
NM_004936.4
p.C74Y
c.221G>A
1 paper
NM_004936.4
p.T79A
c.235A>G
1 paper
NM_004936.4
p.T79I
c.236C>T
2 papers
NM_004936.4
p.N73S
c.218A>G
1 paper
NM_004936.4
p.L80P
c.239T>C
1 paper
NM_004936.4
p.P72R
c.215C>G
1 paper
NM_004936.4
p.T81I
c.242C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."