Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.A70insFs

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.A70insFs
c.209_210insG
Surrounding Variants
4 papers
NM_004936.4
p.A70V
c.209C>T
1 paper
NM_004936.4
p.A70T
c.208G>A
3 papers
NM_004936.4
p.E71K
c.211G>A
1 paper
NM_004936.4
p.E71G
c.212A>G
1 paper
NM_004936.4
p.E71D
c.213G>T
1 paper
NM_004936.4
p.G69C
c.205G>T
1 paper
NM_004936.4
p.E71_P72insFs
c.213_214insT
1 paper
NM_004936.4
p.E71D
c.213G>C
2 papers
NM_004936.4
p.G69S
c.205G>A
1 paper
NM_004936.4
p.P72fs
c.214_215fs
1 paper
NM_004936.4
p.P72R
c.215C>G
1 paper
NM_004936.4
p.H68L
c.203A>T
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