Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.H68insFs

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.H68insFs
c.202_203insT
Surrounding Variants
2 papers
NM_004936.4
p.H68Y
c.202C>T
1 paper
NM_004936.4
p.H68N
c.202C>A
1 paper
NM_004936.4
p.H68L
c.203A>T
2 papers
NM_004936.4
p.L67P
c.200T>C
1 paper
NM_004936.4
p.G69C
c.205G>T
2 papers
NM_004936.4
p.G69S
c.205G>A
1 paper
NM_004936.4
p.L66P
c.197T>C
1 paper
NM_004936.4
p.A70T
c.208G>A
1 paper
NM_004936.4
p.L66L
c.196C>T
4 papers
NM_004936.4
p.A70V
c.209C>T
1 paper
NM_004936.4
p.A70insFs
c.209_210insG
1 paper
NM_004936.4
p.L65P
c.194T>C
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