Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.L64R

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_004936.4
p.L64R
c.191T>G
Surrounding Variants
1 paper
NM_004936.4
p.L64P
c.191T>C
1 paper
NM_004936.4
p.L64V
c.190C>G
1 paper
NM_004936.4
p.L65V
c.193C>G
1 paper
NM_004936.4
p.L65P
c.194T>C
1 paper
NM_004936.4
p.E63Q
c.187G>C
1 paper
NM_004936.4
p.E63K
c.187G>A
1 paper
NM_004936.4
p.A62A
c.186G>T
1 paper
NM_004936.4
p.L66L
c.196C>T
1 paper
NM_004936.4
p.L66P
c.197T>C
1 paper
NM_004936.4
p.A62V
c.185C>T
1 paper
NM_004936.4
p.A62P
c.184G>C
2 papers
NM_004936.4
p.L67P
c.200T>C
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