Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.Q52_V53Splc

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.Q52_V53Splc
c.157-4G>A
Surrounding Variants
1 paper
NM_004936.4
p.Q52_V53Splc
c.157-1G>A
1 paper
NM_004936.4
p.V53I
c.157G>A
1 paper
NM_004936.4
p.V53A
c.158T>C
1 paper
NM_004936.4
p.M54T
c.161T>C
1 paper
NM_004936.4
p.M55L
c.163A>T
1 paper
NM_004936.4
p.M55V
c.163A>G
1 paper
NM_004936.4
p.M55L
c.163A>C
1 paper
NM_004936.4
p.M55I
c.165G>T
1 paper
NM_004936.4
p.M55I
c.165G>C
1 paper
NM_004936.4
p.M55I
c.165G>A
3 papers
NM_004936.4
p.Q52_V53Splc
c.157-18C>T
1 paper
NM_004936.4
p.M56I
c.168G>T
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