Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.N44S

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004936.4
p.N44S
c.131A>G
Surrounding Variants
1 paper
NM_004936.4
p.N44H
c.130A>C
1 paper
NM_004936.4
p.R45C
c.133C>T
1 paper
NM_004936.4
p.R45S
c.133C>A
1 paper
NM_004936.4
p.E35_N44del10
c.103_131del30
1 paper
NM_004936.4
p.V43A
c.128T>C
1 paper
NM_004936.4
p.V43I
c.127G>A
1 paper
NM_004936.4
p.F46L
c.136T>C
1 paper
NM_004936.4
p.F46L
c.138C>G
1 paper
NM_004936.4
p.F46L
c.138C>A
2 papers
NM_004936.4
p.N41fs
c.121_122fs
1 paper
NM_004936.4
p.G47E
c.140G>A
3 papers
NM_004936.4
p.N41S
c.122A>G
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