Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.A36_G37del2

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.A36_G37del2
c.106_110del6
Surrounding Variants
1 paper
NM_004936.4
p.A38A
c.114G>A
1 paper
NM_004936.4
p.A38S
c.112G>T
1 paper
NM_004936.4
p.A38T
c.112G>A
1 paper
NM_004936.4
p.P40S
c.118C>T
3 papers
NM_004936.4
p.P40T
c.118C>A
1 paper
NM_004936.4
p.G37S
c.109G>A
1 paper
NM_004936.4
p.A36V
c.107C>T
6 papers
NM_004936.4
p.N41D
c.121A>G
1 paper
NM_004936.4
p.N41H
c.121A>C
3 papers
NM_004936.4
p.N41S
c.122A>G
2 papers
NM_004936.4
p.N41fs
c.121_122fs
1 paper
NM_004936.4
p.E35E
c.105A>G
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