Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.L33R

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_004936.4
p.L33R
c.98T>G
Surrounding Variants
1 paper
NM_004936.4
p.L33F
c.97C>T
1 paper
NM_004936.4
p.Q32*
c.94C>T
2 papers
NM_004936.4
p.E35*
c.103G>T
1 paper
NM_004936.4
p.E35K
c.103G>A
1 paper
NM_004936.4
p.E35E
c.105A>G
1 paper
NM_004936.4
p.V30E
c.89T>A
1 paper
NM_004936.4
p.A36V
c.107C>T
1 paper
NM_004936.4
p.G37S
c.109G>A
1 paper
NM_004936.4
p.A38S
c.112G>T
1 paper
NM_004936.4
p.E28fs
c.82_83fs
1 paper
NM_004936.4
p.A38T
c.112G>A
1 paper
NM_004936.4
p.E28delFs
c.82delC
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