Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.D15E

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.D15E
c.45T>A
Surrounding Variants
1 paper
NM_004936.4
p.G12_D15delFs
c.35_44del10
1 paper
NM_004936.4
p.E16A
c.47A>C
1 paper
NM_004936.4
p.D15_E16delFs
c.43_46del4
1 paper
NM_004936.4
p.E16E
c.48G>A
1 paper
NM_004936.4
p.G17R
c.49G>C
1 paper
NM_004936.4
p.G13V
c.38G>T
7 papers
NM_004936.4
p.G13D
c.38G>A
1 paper
NM_004936.4
p.G12_G13delFs
c.36_37delCG
2 papers
NM_004936.4
p.L18V
c.52C>G
3 papers
NM_004936.4
p.G13C
c.37G>T
3 papers
NM_004936.4
p.G13R
c.37G>C
9 papers
NM_004936.4
p.G12V
c.35G>T
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