Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.M8L

CDKN2B

718 papers

RefSeq Summary

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which...

Pfam Domains

Ank_2aa 18–110UCSCAnkyrin repeats (3 copies)

Gene Aliases

HGNC Name

cyclin dependent kinase inhibitor 2B

HGNC Alias Symbols

P15; MTS2; INK4B; TP15; CDK4I; p15INK4b

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004936.4
p.M8L
c.22A>T
Surrounding Variants
1 paper
NM_004936.4
p.M8L
c.22A>C
2 papers
NM_004936.4
p.M8R
c.23T>G
2 papers
NM_004936.4
p.M8I
c.24G>T
2 papers
NM_004936.4
p.M8I
c.24G>C
1 paper
NM_004936.4
p.G7A
c.20G>C
2 papers
NM_004936.4
p.M8I
c.24G>A
1 paper
NM_004936.4
p.G7D
c.20G>A
1 paper
NM_004936.4
p.P9S
c.25C>T
1 paper
NM_004936.4
p.M1_G7del7
c.1_20del21
1 paper
NM_004936.4
p.S10R
c.28A>C
1 paper
NM_004936.4
p.S10T
c.29G>C
1 paper
NM_004936.4
p.S10R
c.30T>G
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